Colts Game Sunday: Colts vs Rams odds and prediction for NFL Week 2 Game

INDIANAPOLIS, INDIANA - SEPTEMBER 12: Carson Wentz #2 of the Indianapolis Colts (Photo by Justin Casterline/Getty Images)
INDIANAPOLIS, INDIANA - SEPTEMBER 12: Carson Wentz #2 of the Indianapolis Colts (Photo by Justin Casterline/Getty Images) /

The Indianapolis Colts had a tough test in front of them in their season opener, as they had to take on a Seahawks team that featured one of the best combinations of wide receivers in this game. Ultimately, it was too much for Carson Wentz and a somewhat patchwork offensive line to overcome.

Russell Wilson led Seattle to the win by tossing four touchdown passes, as offensive coordinator Shane Waldron completely outschemed Matt Eberflus by tearing apart his 2-high safety looks. Wentz had his moments, as he tossed two touchdown passes, but he left plenty of meat on the bone.

There’s no time for the Colts to mope around and lick their wounds, as they have a matchup against a Los Angeles Rams team that is fresh off taking the Bears behind the woodshed in a dominant performance. An 0-2 start might actually happen if Frank Reich doesn’t prepare well enough.

Will the Colts be able to pull off a big upset on the back of Wentz taking it to the Los Angeles defense? Or will a Super Bowl contender in LA flex their muscles?

Colts vs Rams Odds Week 2

According to our friends at WynnBet, the Rams are favored -200 on the money line (bet $200 to win $100), while the Colts come in at +170 (bet $100 to win $170). If you prefer to bet the spread, Los Angeles has -110 odds to cover -4.0, while Indianapolis has the same -110 odds to make up that +4.0 difference.

The over/under for Sunday’s game is set at 47.5, with the over getting -110 odds and the under coming in exactly the same at -110.

Colts vs Rams Prediction Week 2

The Rams look like a team that will contend for a championship. Yes, they played against Andy Dalton, but they were much more dominant than the scoreline indicated. While the Colts are no pushover, there are huge obstacles that Indy will need to overcome on both sides of the ball.

While the Rams don’t have the best run defense in the world, the Colts will have a tough time getting separation against Jalen Ramsey while keeping Aaron Donald out of the backfield if Wentz continues to hold onto the ball for as long as he did in the Seattle game. Quenton Nelson can only do so much.

Given how lackluster the division is, Indy shouldn’t feel that an 0-2 start is the end of the world. However, that record could become reality, as the Rams have stars at nearly every position to counteract Indianapolis. It’ll take some luck to get the win here, especially if Matthew Stafford and that offense go crazy again.

Rams 31, Colts 20

Make your pick now on WynnBet.