6. Ryan Diem
Northern Illinois isn't exactly known for its ability to produce NFL talent but the Colts drafted Ryan Diem out of the university in 2001 and he went on to spend 11 years in the NFL, all spent in Indianapolis. Diem started 150 games at right tackle and was on the Super Bowl winning squad in the 2006 season.
5. Cato June
In the sixth round of the 2003 NFL Draft, Cato June joined the Colts out of Michigan. He only appeared in 11 games as a rookie but in Year 2, June exploded onto the scene, tallying 110 tackles in 16 starts.
In 2005, June's third year in the league, he made the only Pro Bowl of his career after recording 103 tackles, seven defended passes, and five interceptions, two of which were returned for touchdowns. June not only made the Pro Bowl but he was nearly crowned All-Pro, finishing second in the voting.
June played for the Colts for four years total, including the year they won it all in the 2006 season. He finished his career with stints in Tampa Bay and Chicago.