1. Colts have to minimize mistakes in all three phases of the game
Indianapolis' losses this season tend to share some common themes: lots of turnovers, killer penalties, and avoidable errors. Against the Bengals, QB Gardner Minshew was intercepted on a wild play, Isaiah McKenzie muffed a punt after getting run over by his own teammate, and Matt Gay missed a 38-yard field goal try. These types of mistakes are costly and could prove fatal to the Colts' playoff chances.
On paper, Indianapolis should be favorites this week. Pittsburgh has lost three of their last four games including defeats to the Patriots and Cardinals who each only have three wins this season. The Steelers, who still don't have their usual starting QB, haven't scored more than 20 points in four straight games, while the Colts have only failed to hit that mark twice all year.
However, there’s nothing more detrimental to the favored team than losing focus and beating themselves. Pittsburgh may be dealing with its fair share of problems, but this team is still dangerous enough to snatch a win on the road if the Colts leave the door open.