2. Stop Rams receiving core, including Puka Nacua
Indianapolis dodges a bullet with the lack of Cooper Kupp in this game for Los Angeles, but this Colts' defense will still have their work cut out for them and then some this Sunday. The Rams have a great balance of speed, size, and elite route-running in this receiving core, and all of these receivers will be a problem.
The biggest problem, in all likelihood, will be Puka Nacua, who has completely burst on the scene in the absence of Kupp, his targets in his first two games are the most in NFL history, and he has taken advantage of his opportunities with 30 receptions and 338 yards on the season. He has not hit the endzone yet, so he will be looking to do that against the Colts, and he will be tough to stop from doing so.
This secondary will also have to deal with players like Tutu Atwell and Van Jefferson, who have great speed and could burn a corner at a moment's notice. While inconsistent, guys like these are absolute playmakers that make stopping them very hard to get done. Ben Skowronek finds his way to get used in the slot while also getting his opportunity as a gadget guy when need be, so keeping an eye on him as a playmaker will also be key.
While a bit past his prime, Matthew Stafford has still had his fair share of solid moments this season spreading the ball to these receivers, so keeping this whole unit in check will be key to picking up a win against the Rams.