The Indianapolis Colts' defense has been able to survive so far without slot corner Kenny Moore II. Moore is one of the best players at his position in the NFL, but Indy has played a couple of teams with dud offenses. That is unlikely to change in Week 6.
The Arizona Cardinals, even if quarterback Kyler Murray plays (he is questionable with a foot injury), haven't been explosive or productive this season. Murray can run around the pocket extremely well, but he seems incapable of consistently leading his team to loads of points.
Indianapolis' Moore won't face Murray and the Cardinals, though, as he has been ruled out for the third straight game with an Achilles injury. In his place will likely be Chris Lammons, and that's fine in a pinch. Eventually, Moore is going to be needed, but sitting out now is maybe better for the season overall.
Indianapolis Colts will need Kenny Moore II before the season is over
Moore understands that, too. According to Joel A. Erickson of the Journal and Courier, the cornerback said, "It’s so delicate of an injury, and an area to have such an injury, there’s such pressure in that spot. It’s just all hands on deck to try to get me back out there. I’ve got to do all I can from a player standpoint to get back out there...Physically, I’m getting there."
The cornerback also confirmed that mentally, he is fine, too. He doesn't like being forced to sit out games, but rushing back could only make his injury worse, and that could cost him the rest of the season. The player and the Indianapolis Colts don't want that.
To be fair, Moore could probably miss a couple more games, and Indy would probably be OK. In Week 7, Indianapolis plays the Los Angeles Chargers, who are scuffling a bit offensively (LA is 26th in the NFL at 19.6 points per game). In Week 8, the Colts play the weak Tennessee Titans again.
After that, however, things begin to get much tougher for Indianapolis defensively. From Week 9 onward, Indy will face a bunch of teams with good offenses, such as the Pittsburgh Steelers, Seattle Seahawks, Houston Texans (twice), Kansas City Chiefs, and Jacksonville Jaguars (twice).
Before the season is over, the Indianapolis Colts are going to need Kenny Moore II, and need him to stay healthy. It is better to have him out now and back ready to go by Week 9. The Colts have a great chance at a playoff push and a run once there, and Moore will be needed to be a part of that.