Colts vs Jaguars best bets for Week 2 of 2022 NFL season

Are you ready for some FOOTBALL?! Football that doesn’t end in a TIE?!? Indianapolis Colts fans entered Week 1 with a new quarterback yet again in 2022, and saw Matt Ryan lead a furious comeback from the brink, only for overtime to end up fruitless for both sides.

But there were positives! There was a glint in the eyes of every Colts fan during that fourth quarter! And without an Alec Pierce drop and some Rodrigo Blankenship sadness, things might’ve turned out very differently.

This week, Indianapolis turns their eyes to the Jacksonville Jaguars, looking for a bizarre form of payback for last season’s Week 18 playoff-ruining face plant.

After all, Carson Wentz isn’t here anymore, so he won’t be looking to exact any kind of revenge. He’s got his own thing to command.

But the Colts still have a metallic taste in their mouths after the Jaguars routed them and knocked them out of the playoff picture last season, and old buddies Frank Reich and Doug Pederson will be fully taking aim at one another this time around.

If you don’t want to be left out in the cold kicking by yourself like Rodrigo, you might want to try these best bets.

Best Colts bets Week 2

*All Odds Courtesy of FanDuel on Friday afternoon Sept. 16, and subject to change*

3. Colts Moneyline -198

After Indianapolis finally found their mojo at the tail end of Week 1, they’ll be looking to put their stamp on the 2022 season with a road victory over Jacksonville (two straight road games?!) immediately following a late Jags implosion in Washington.

That’s right. Carson Wentz actually got his revenge already. And Indy’s will taste just as sweet.

2. First Touchdown Scorer: Michael Pittman Jr., +800

The unorthodox choice, but Pittman Jr. had a coming out party last week with Matty Ice at the helm, racking up 121 yards and a score on nine catches. The Jaguars are another suspect secondary held together by tape and memories of 2017, and Pittman has much juicier odds on First TD than on Anytime TD (a modest +135). Put some dough on both, if you’re a thrill seeker.

1. Jonathan Taylor to Score 2+ TDs (+250)

Picking any specific player to reach the end zone twice is always a dicey proposition, but is anyone a better bet to do so than Taylor, Indy’s unstoppable train who does nothing but chug along? It’s always more fun to root for Taylor scores and an offensive splash than to root against those things. Bottom line.