3 best prop bets for Colts vs 49ers Week 7 Sunday Night Football matchup

It seems like the Indianapolis Colts are hit with a devastating injury every week.

Leading up to their Week 7 clash against San Francisco, however, the Colts received two doses of gutting injury news.

First, it was reported that Parris Campbell will miss significant time with a foot injury he sustained in the win over Houston. Just a couple days later, we learned that Julian Blackmon, an emerging star at the safety position, suffered a torn Achilles in Wednesday’s practice and is out for the season.

The Colts have embraced the next man up philosophy all season, and they’ll need all hands on deck for their Sunday Night Football clash vs the 49ers, who will be returning some key starters themselves, including Jimmy Garoppolo.

Injuries aside, this figures to be a compelling game between two teams that need a victory in the worst way. Taking that — plus the primetime allure — into account, let’s highlight some juicy prop bets fans should consider taking.

All odds listed come courtesy of WynnBET.

3 best prop bets for Colts vs 49ers in Week 7

3. Colts over 20.5 points scored (+105)

Wait, what? We know the Colts rank in the bottom third in the league in points scored per game, but 20.5 points seems disrespectful given the way Carson Wentz has performed this season. Not to mention, Jonathan Taylor is coming off his best game of the year. More on him in a minute.

For now, let’s focus our attention on Wentz.

The Colts quarterback is completing 64.2% of his passes for 257.5 yards per game and nine touchdowns to one interception. He’s playing about as good as fans could’ve asked for given the injuries to the offensive line.

Additionally, the 49ers have allowed 21 or more points in all but two games this season. That included letting the winless Lions post 33 points in Week 1. You mean to tell us the Colts can’t score 21 or more points on this defense?

All folks need for this bet — which comes with +105 odds (bet $100 to win $105) — to cash is three touchdowns or two touchdowns and three field goals. Seems easy enough, right? We think so, as the Colts’ offense is humming right now, averaging 27.6 points over their last three contests.