Part of having James being out also means the Colts should want to throw the ball down the field. Brissett has a really strong arm, and taking some shots down the field would keep the Chargers defense off guard. That might be the biggest key of all.
The Chargers will likely be playing a lot of one-on-one coverage on the outside. That means T.Y. Hilton and Parris Campbell will have opportunities to go deep. That is going to be needed to stretch the defense and open up the running game even more.
I’m not expecting Brissett to have an all-world game throwing the football, but a few deep shots are paramount in their success on Sunday. Even if they don’t complete a ton of deep balls, throwing them at least makes the defense play back a little bit.
Having Brissett throw the ball from the pocket down the field is going to be key. The offensive line needs to block well against some good pass rushers from the Chargers defensive line. They need to perform better than they did in the preseason.
Hopefully the Colts are able to do all three of these things. If they are able to execute all of these aspects of the game, they will win the game on Sunday.