In the 2012 Draft, Grigson had ten picks at his disposal, including the first overall pick which was used on Andrew Luck. Below are the ten picks he made.
- Quarterback Andrew Luck (1st overall)
- Tight end Coby Fleener (34th overall)
- Tight end Dwayne Allen (64th overall)
- Wide receiver T.Y. Hilton (92nd overall)
- Defensive tackle Josh Chapman (136th overall)
- Running back Vick Ballard (170th overall)
- Wide receiver LaVon Brazill (206th overall)
- Guard Justin Anderson (208th overall)
- Defensive end Tim Fugger (214th overall)
- Quarterback Chandler Harnish (253rd overall)
While the first four picks, Luck, Fleener, Allen, and Hilton, have all been at least solid NFL players, none of the late round picks made by Grigson had any NFL success.
Chapman flamed out of the NFL after making 29 appearances with the Colts, Ballard struggled with injuries after his rookie season, Brazil showed some flashes of greatness before being suspended twice for violating the substance policy, and Anderson, Fugger, and Harnish never made an appearance for the Colts.
Luck and Hilton are the two main pieces of the Colts’ offense to this day, and were definitely great picks by Grigson. Grigson drafted two solid tight ends in Fleener and Allen, but it was a bit of a head scratcher to draft two tight ends so early in the draft. This was arguably Grigson’s best draft as the general manager of the Colts, yet only two of the players are still on the Colts, and only four of the players are still in the NFL.